Detalhe da pesquisa
1.
Japan-Multimodal Intervention Trial for the Prevention of Dementia: A randomized controlled trial.
Alzheimers Dement
; 2024 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38646854
2.
Presenilin: A Multi-Functional Molecule in the Pathogenesis of Alzheimer's Disease and Other Neurodegenerative Diseases.
Int J Mol Sci
; 25(3)2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38339035
3.
Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
J Neurosci
; 42(8): 1574-1586, 2022 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34987110
4.
Apolipoprotein E4 inhibits γ-secretase activity via binding to the γ-secretase complex.
J Neurochem
; 164(6): 858-874, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36582176
5.
Alzheimer's Amyloid ß Peptide Induces Angiogenesis in an Alzheimer's Disease Model Mouse through Placental Growth Factor and Angiopoietin 2 Expressions.
Int J Mol Sci
; 24(5)2023 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36901941
6.
Deletion of UCP1 in Tg2576 Mice Increases Body Temperature and Exacerbates Alzheimer's Disease-Related Pathologies.
Int J Mol Sci
; 24(3)2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36769062
7.
High temperature promotes amyloid ß-protein production and γ-secretase complex formation via Hsp90.
J Biol Chem
; 295(52): 18010-18022, 2020 12 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33067321
8.
Oral dysfunctions and cognitive impairment/dementia.
J Neurosci Res
; 99(2): 518-528, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33164225
9.
Comparison of the Physical Characteristics and Behavior in ABC Transporter A1, A7 or Apolipoprotein E Knockout Mice with Lipid Transport Dysfunction.
Biol Pharm Bull
; 44(12): 1851-1859, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34853267
10.
A clinical dose of angiotensin-converting enzyme (ACE) inhibitor and heterozygous ACE deletion exacerbate Alzheimer's disease pathology in mice.
J Biol Chem
; 294(25): 9760-9770, 2019 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31072831
11.
Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer's pathology.
Proc Natl Acad Sci U S A
; 114(14): E2947-E2954, 2017 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28320965
12.
Iron treatment inhibits Aß42 deposition in vivo and reduces Aß42/Aß40 ratio.
Biochem Biophys Res Commun
; 512(4): 653-658, 2019 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30791980
13.
Nasal obstruction during adolescence induces memory/learning impairments associated with BDNF/TrkB signaling pathway hypofunction and high corticosterone levels.
J Neurosci Res
; 96(6): 1056-1065, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29392750
14.
Molar loss and powder diet leads to memory deficit and modifies the mRNA expression of brain-derived neurotrophic factor in the hippocampus of adult mice.
BMC Neurosci
; 17(1): 81, 2016 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27919226
15.
Tooth loss might not alter molecular pathogenesis in an aged transgenic Alzheimer's disease model mouse.
Gerodontology
; 33(3): 308-14, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25243637
16.
Involvement of cdc42/Rho kinase in apoA-I-mediated cholesterol efflux through interaction between cytosolic lipid-protein particles and microtubules in rat astrocytes.
J Neurosci Res
; 92(4): 455-63, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24446142
17.
Liquid diet induces memory impairment accompanied by a decreased number of hippocampal neurons in mice.
J Neurosci Res
; 92(8): 1010-7, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24687840
18.
Aß43 is the earliest-depositing Aß species in APP transgenic mouse brain and is converted to Aß41 by two active domains of ACE.
Am J Pathol
; 182(6): 2322-31, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23562443
19.
[Role of apolipoprotein E in the molecular pathomechanism of Alzheimer disease].
Nihon Shinkei Seishin Yakurigaku Zasshi
; 34(1): 5-9, 2014 Feb.
Artigo
em Japonês
| MEDLINE | ID: mdl-25069266
20.
[Periodontal disease].
Nihon Rinsho
; 72(4): 744-8, 2014 Apr.
Artigo
em Japonês
| MEDLINE | ID: mdl-24796109